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Application of Design of Experiment and Simulation Methods to Liquid Chromatography Analysis of Topical HIV Microbicides Stampidine and HI443
This study intended to determine if experimental design and Monte Carlo simulation methods can be utilized to optimize the liquid chromatography (LC) analysis of active molecules. The method was applied for the simultaneous analysis of two topical microbicides, stampidine (STP) and HI443 in bulk and...
Autores principales: | Agrahari, Vivek, Meng, Jianing, Zhang, Tao, Youan, Bi-Botti C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354943/ https://www.ncbi.nlm.nih.gov/pubmed/25767739 http://dx.doi.org/10.4172/2155-9872.1000180 |
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