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Quantification of cell identity from single-cell gene expression profiles

The definition of cell identity is a central problem in biology. While single-cell RNA-seq provides a wealth of information regarding cell states, better methods are needed to map their identity, especially during developmental transitions. Here, we use repositories of cell type-specific transcripto...

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Detalles Bibliográficos
Autores principales: Efroni, Idan, Ip, Pui-Leng, Nawy, Tal, Mello, Alison, Birnbaum, Kenneth D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354993/
https://www.ncbi.nlm.nih.gov/pubmed/25608970
http://dx.doi.org/10.1186/s13059-015-0580-x