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MicroRNA-181b regulates endotoxin tolerance by targeting IL-6 in macrophage RAW264.7 cells

Interleukin 6 (IL-6) is a major pro-inflammatory cytokine and dysregulation of IL-6 is relevant to many inflammatory diseases. Endotoxin induced tolerance of IL-6 is an important mechanism to avoid the excessive immune reaction. But to date, the molecular mechanisms of endotoxin tolerance of IL-6 re...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjun, Shen, Xiaojun, Xie, Luyang, Chu, Maoping, Ma, Yanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355005/
https://www.ncbi.nlm.nih.gov/pubmed/25762865
http://dx.doi.org/10.1186/s12950-015-0061-8