Cargando…
Nitric Oxide Prevents Alveolar Senescence and Emphysema in a Mouse Model
N(ω)-nitro-L-arginine methyl ester (L-NAME) treatment induces arteriosclerosis and vascular senescence. Here, we report that the systemic inhibition of nitric oxide (NO) production by L-NAME causes pulmonary emphysema. L-NAME-treated lungs exhibited both the structural (alveolar tissue destruction)...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355068/ https://www.ncbi.nlm.nih.gov/pubmed/25756287 http://dx.doi.org/10.1371/journal.pone.0116504 |