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Hydrocortisone enhances the barrier properties of HBMEC/ciβ, a brain microvascular endothelial cell line, through mesenchymal-to-endothelial transition-like effects

BACKGROUND: Because in vitro blood–brain barrier (BBB) models are important tools for studying brain diseases and drug development, we recently established a new line of conditionally immortalized human brain microvascular endothelial cells (HBMEC/ciβ) for use in such models. Since one of the most i...

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Detalles Bibliográficos
Autores principales: Furihata, Tomomi, Kawamatsu, Shinya, Ito, Ryo, Saito, Kosuke, Suzuki, Shota, Kishida, Satoshi, Saito, Yoshiro, Kamiichi, Atsuko, Chiba, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355132/
https://www.ncbi.nlm.nih.gov/pubmed/25763180
http://dx.doi.org/10.1186/s12987-015-0003-0