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Similarity-based search of model organism, disease and drug effect phenotypes

BACKGROUND: Semantic similarity measures over phenotype ontologies have been demonstrated to provide a powerful approach for the analysis of model organism phenotypes, the discovery of animal models of human disease, novel pathways, gene functions, druggable therapeutic targets, and determination of...

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Detalles Bibliográficos
Autores principales: Hoehndorf, Robert, Gruenberger, Michael, Gkoutos, Georgios V, Schofield, Paul N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355138/
https://www.ncbi.nlm.nih.gov/pubmed/25763178
http://dx.doi.org/10.1186/s13326-015-0001-9