Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin degrading enzyme

CC chemokine ligands (CCL) are 8-14 kDa signaling proteins involved in diverse immune functions. While CCLs share similar tertiary structures, oligomerization produces highly diverse quaternary structures that protect chemokines from proteolytic degradation and modulate their functions. CCL18 is clo...

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Detalles Bibliográficos
Autores principales: Liang, Wenguang G, Ren, Min, Zhao, Fan, Tang, Wei-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355285/
https://www.ncbi.nlm.nih.gov/pubmed/25636406
http://dx.doi.org/10.1016/j.jmb.2015.01.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355285/
https://www.ncbi.nlm.nih.gov/pubmed/25636406
http://dx.doi.org/10.1016/j.jmb.2015.01.012

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