Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition

BACKGROUND: Amyloid β (Aβ) peptide is hypothesized to stimulate microglia to acquire their characteristic proinflammatory phenotype in Alzheimer’s disease (AD) brains. The specific mechanisms by which Aβ leads to microglial activation remain an area of interest for identifying attractive molecular t...

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Detalles Bibliográficos
Autores principales: Rojanathammanee, Lalida, Floden, Angela M, Manocha, Gunjan D, Combs, Colin K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355356/
https://www.ncbi.nlm.nih.gov/pubmed/25889879
http://dx.doi.org/10.1186/s12974-015-0255-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355356/
https://www.ncbi.nlm.nih.gov/pubmed/25889879
http://dx.doi.org/10.1186/s12974-015-0255-2

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