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CCAAT/enhancer-binding protein β promotes receptor activator of nuclear factor-kappa-B ligand (RANKL) expression and osteoclast formation in the synovium in rheumatoid arthritis

INTRODUCTION: CCAAT/enhancer-binding protein β (C/EBPβ) is a transcription factor that is activated in the synovium in rheumatoid arthritis (RA) and promotes expression of various matrix metalloproteinases. In this study, we examined whether C/EBPβ mediates the expression of receptor activator of nu...

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Detalles Bibliográficos
Autores principales: Tsushima, Hidetoshi, Okazaki, Ken, Ishihara, Kohei, Ushijima, Takahiro, Iwamoto, Yukihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355365/
https://www.ncbi.nlm.nih.gov/pubmed/25811130
http://dx.doi.org/10.1186/s13075-015-0532-6