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Changes in Retinal Function and Morphology Are Early Clinical Signs of Disease in Cattle with Bovine Spongiform Encephalopathy

Bovine spongiform encephalopathy (BSE) belongs to a group of fatal, transmissible protein misfolding diseases known as transmissible spongiform encephalopathies (TSEs). All TSEs are caused by accumulation of misfolded prion protein (PrP(Sc)) throughout the central nervous system (CNS), which results...

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Detalles Bibliográficos
Autores principales: West Greenlee, M. Heather, Smith, Jodi D., Platt, Ekundayo M., Juarez, Jessica R., Timms, Leo L., Greenlee, Justin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355414/
https://www.ncbi.nlm.nih.gov/pubmed/25756286
http://dx.doi.org/10.1371/journal.pone.0119431