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Contact-mediated intracellular delivery of hydrophobic drugs from polymeric nanoparticles
Encapsulation of drugs in nanoparticles can enhance the accumulation of drugs in tumours, reduce toxicity toward healthy tissue, and improve pharmacokinetics compared to administration of free drug. To achieve efficient delivery and release of drugs at the target site, mechanisms of interaction betw...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355425/ https://www.ncbi.nlm.nih.gov/pubmed/25774230 http://dx.doi.org/10.1186/s12645-014-0008-4 |