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Estrogen regulates T helper 17 phenotype and localization in experimental autoimmune arthritis

INTRODUCTION: The incidence and progression of many autoimmune diseases are sex-biased, which might be explained by the immunomodulating properties of endocrine hormones. Treatment with estradiol potently inhibits experimental autoimmune arthritis. Interleukin-17-producing T helper cells (Th17) are...

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Detalles Bibliográficos
Autores principales: Andersson, Annica, Stubelius, Alexandra, Karlsson, Merja Nurkkala, Engdahl, Cecilia, Erlandsson, Malin, Grahnemo, Louise, Lagerquist, Marie K, Islander, Ulrika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355457/
https://www.ncbi.nlm.nih.gov/pubmed/25888974
http://dx.doi.org/10.1186/s13075-015-0548-y