Spatial Positioning of All 24 Chromosomes in the Lymphocytes of Six Subjects: Evidence of Reproducible Positioning and Spatial Repositioning following DNA Damage with Hydrogen Peroxide and Ultraviolet B

The higher-order organization of chromatin is well-established, with chromosomes occupying distinct positions within the interphase nucleus. Chromatin is susceptible to, and constantly assaulted by both endogenous and exogenous threats. However, the effects of DNA damage on the spatial topology of c...

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Detalles Bibliográficos
Autores principales: Ioannou, Dimitrios, Kandukuri, Lakshmi, Quadri, Ameer, Becerra, Victor, Simpson, Joe Leigh, Tempest, Helen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355486/
https://www.ncbi.nlm.nih.gov/pubmed/25756782
http://dx.doi.org/10.1371/journal.pone.0118886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355486/
https://www.ncbi.nlm.nih.gov/pubmed/25756782
http://dx.doi.org/10.1371/journal.pone.0118886

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