Cargando…
Voltage-gated sodium channels in the mammalian heart
Mammalian species express nine functional voltage-gated Na(+) channels. Three of them, the cardiac-specific isoform Na(v)1.5 and the neuronal isoforms Na(v)1.8 and Na(v)1.9, are relatively resistant to the neurotoxin tetrodotoxin (TTX; IC(50) ≥ 1 μM). The other six isoforms are highly sensitive to T...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bloomsbury Qatar Foundation Journals
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355518/ https://www.ncbi.nlm.nih.gov/pubmed/25780798 http://dx.doi.org/10.5339/gcsp.2014.58 |