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Voltage-gated sodium channels in the mammalian heart

Mammalian species express nine functional voltage-gated Na(+) channels. Three of them, the cardiac-specific isoform Na(v)1.5 and the neuronal isoforms Na(v)1.8 and Na(v)1.9, are relatively resistant to the neurotoxin tetrodotoxin (TTX; IC(50) ≥ 1 μM). The other six isoforms are highly sensitive to T...

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Detalles Bibliográficos
Autores principales:	Zimmer, Thomas, Haufe, Volker, Blechschmidt, Steve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bloomsbury Qatar Foundation Journals 2014
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355518/ https://www.ncbi.nlm.nih.gov/pubmed/25780798 http://dx.doi.org/10.5339/gcsp.2014.58

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