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CXC Chemokines Function as a Rheostat for Hepatocyte Proliferation and Liver Regeneration

BACKGROUND: Our previous in vitro studies have demonstrated dose-dependent effects of CXCR2 ligands on hepatocyte cell death and proliferation. In the current study, we sought to determine if CXCR2 ligand concentration is responsible for the divergent effects of these mediators on liver regeneration...

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Detalles Bibliográficos
Autores principales: Wilson, Gregory C., Kuboki, Satoshi, Freeman, Christopher M., Nojima, Hiroyuki, Schuster, Rebecca M., Edwards, Michael J., Lentsch, Alex B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355613/
https://www.ncbi.nlm.nih.gov/pubmed/25756662
http://dx.doi.org/10.1371/journal.pone.0120092