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Sumoylation of CCAAT/enhancer-binding protein α is implicated in hematopoietic stem/progenitor cell development through regulating runx1 in zebrafish

The small ubiquitin-related modifier (SUMO) participates in various cellular processes, including maintenance of genome integrity, nuclear transport, transcription and signal transduction. However, the biological function of sumoylation in hematopoiesis has not been fully explored. We show here that...

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Detalles Bibliográficos
Autores principales: Yuan, Hao, Zhang, Tao, Liu, Xiaohui, Deng, Min, Zhang, Wenqing, Wen, Zilong, Chen, Saijuan, Chen, Zhu, de The, Hugues, Zhou, Jun, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355724/
https://www.ncbi.nlm.nih.gov/pubmed/25757417
http://dx.doi.org/10.1038/srep09011