Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway

Defect in apoptosis has been implicated as a major cause of resistance to chemotherapy observed in B cell chronic lymphocytic leukaemia (B CLL). This study evaluated the pro-apoptotic effect of an anthocyanin-rich dietary bilberry extract (Antho 50) on B CLL cells from 30 patients and on peripheral...

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Detalles Bibliográficos
Autores principales: Alhosin, Mahmoud, León-González, Antonio J., Dandache, Israa, Lelay, Agnès, Rashid, Sherzad K., Kevers, Claire, Pincemail, Joël, Fornecker, Luc-Matthieu, Mauvieux, Laurent, Herbrecht, Raoul, Schini-Kerth, Valérie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355738/
https://www.ncbi.nlm.nih.gov/pubmed/25757575
http://dx.doi.org/10.1038/srep08996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355738/
https://www.ncbi.nlm.nih.gov/pubmed/25757575
http://dx.doi.org/10.1038/srep08996

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