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N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions
RNA-binding proteins control many aspects of cellular biology through binding single-stranded RNA binding motifs (RBM)(1-3). However, RBMs can be buried within their local RNA structures(4-7), thus inhibiting RNA-protein interactions. N(6)-methyladenosine (m(6)A), the most abundant and dynamic inter...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355918/ https://www.ncbi.nlm.nih.gov/pubmed/25719671 http://dx.doi.org/10.1038/nature14234 |