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Activation of κ-opioid receptor by U50,488H improves vascular dysfunction in streptozotocin-induced diabetic rats

BACKGROUND: Evidence suggests that activation of κ-opioid receptor (KOR) by U50,488H exhibits potential cardiovascular protective properties. However, the effects of U50,488H on vascular dysfunction in diabetes mellitus (DM) are still not clear. The present study was designed to investigate the effe...

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Detalles Bibliográficos
Autores principales: Zhou, Xuan, Wang, Dongjuan, Zhang, Yuyang, Zhang, Jinxia, Xiang, Dingcheng, Wang, Haichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355970/
https://www.ncbi.nlm.nih.gov/pubmed/25887435
http://dx.doi.org/10.1186/s12902-015-0004-7