Cargando…
Activation of κ-opioid receptor by U50,488H improves vascular dysfunction in streptozotocin-induced diabetic rats
BACKGROUND: Evidence suggests that activation of κ-opioid receptor (KOR) by U50,488H exhibits potential cardiovascular protective properties. However, the effects of U50,488H on vascular dysfunction in diabetes mellitus (DM) are still not clear. The present study was designed to investigate the effe...
Autores principales: | Zhou, Xuan, Wang, Dongjuan, Zhang, Yuyang, Zhang, Jinxia, Xiang, Dingcheng, Wang, Haichang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355970/ https://www.ncbi.nlm.nih.gov/pubmed/25887435 http://dx.doi.org/10.1186/s12902-015-0004-7 |
Ejemplares similares
-
Evaluation of Antinociceptive Effects of Chitosan-Coated Liposomes Entrapping the Selective Kappa Opioid Receptor Agonist U50,488 in Mice
por: Mititelu Tartau, Liliana, et al.
Publicado: (2021) -
The kappa opioid receptor agonist U50,488H did not affect brain-stimulation reward while it elicited conditioned place aversion in mice
por: Huang, Peng, et al.
Publicado: (2020) -
Optimisation of the Anti-Trypanosoma brucei Activity of the Opioid Agonist U50488
por: Smith, Victoria C, et al.
Publicado: (2011) -
The κ-Opioid Receptor Agonist U50488H Ameliorates Neuropathic Pain Through the Ca(2+)/CaMKII/CREB Pathway in Rats
por: Zhang, Xiao-Min, et al.
Publicado: (2022) -
Cardioprotection by kappa-opioid receptor agonist U50488H is mediated by opioidergic regulation but not by calcium current modulation
por: Chun, Kook Jin, et al.
Publicado: (2010)