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Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study

BACKGROUND: Impaired regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to vascular complications in patients with type 1 diabetes. We investigated associations between plasma MMP-1, −2, −3, −9, −10 and TI...

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Detalles Bibliográficos
Autores principales: Peeters, Stijn A, Engelen, Lian, Buijs, Jacqueline, Chaturvedi, Nish, Fuller, John H, Schalkwijk, Casper G, Stehouwer, Coen D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355971/
https://www.ncbi.nlm.nih.gov/pubmed/25848912
http://dx.doi.org/10.1186/s12933-015-0195-2