Differential Reprogramming of Isogenic Colorectal Cancer Cells by Distinct Activating KRAS Mutations

[Image: see text] Oncogenic mutations of Ras at codons 12, 13, or 61, that render the protein constitutively active, are found in ∼16% of all cancer cases. Among the three major Ras isoforms, KRAS is the most frequently mutated isoform in cancer. Each Ras isoform and tumor type displays a distinct p...

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Detalles Bibliográficos
Autores principales: Hammond, Dean E., Mageean, Craig J., Rusilowicz, Emma V., Wickenden, Julie. A., Clague, Michael J., Prior, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356034/
https://www.ncbi.nlm.nih.gov/pubmed/25599653
http://dx.doi.org/10.1021/pr501191a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356034/
https://www.ncbi.nlm.nih.gov/pubmed/25599653
http://dx.doi.org/10.1021/pr501191a

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