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Differential Reprogramming of Isogenic Colorectal Cancer Cells by Distinct Activating KRAS Mutations
[Image: see text] Oncogenic mutations of Ras at codons 12, 13, or 61, that render the protein constitutively active, are found in ∼16% of all cancer cases. Among the three major Ras isoforms, KRAS is the most frequently mutated isoform in cancer. Each Ras isoform and tumor type displays a distinct p...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356034/ https://www.ncbi.nlm.nih.gov/pubmed/25599653 http://dx.doi.org/10.1021/pr501191a |