Vitamin B(12) insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes

BACKGROUND: The dietary supply of methyl donors such as folate, vitamin B(12), betaine, methionine, and choline is essential for normal growth, development, and physiological functions through the life course. Both human and animal studies have shown that vitamin B(12) deficiency is associated with...

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Detalles Bibliográficos
Autores principales: Adaikalakoteswari, Antonysunil, Finer, Sarah, Voyias, Philip D, McCarthy, Ciara M, Vatish, Manu, Moore, Jonathan, Smart-Halajko, Melissa, Bawazeer, Nahla, Al-Daghri, Nasser M, McTernan, Philip G, Kumar, Sudhesh, Hitman, Graham A, Saravanan, Ponnusamy, Tripathi, Gyanendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356060/
https://www.ncbi.nlm.nih.gov/pubmed/25763114
http://dx.doi.org/10.1186/s13148-015-0046-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356060/
https://www.ncbi.nlm.nih.gov/pubmed/25763114
http://dx.doi.org/10.1186/s13148-015-0046-8

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