Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics

Recent studies have indicated that the serotonin receptor subtype 7 (5-HT7R) plays a crucial role in shaping neuronal morphology during embryonic and early postnatal life. Here we show that pharmacological stimulation of 5-HT7R using a highly selective agonist, LP-211, enhances neurite outgrowth in...

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Detalles Bibliográficos
Autores principales: Speranza, Luisa, Giuliano, Teresa, Volpicelli, Floriana, De Stefano, M. Egle, Lombardi, Loredana, Chambery, Angela, Lacivita, Enza, Leopoldo, Marcello, Bellenchi, Gian C., di Porzio, Umberto, Crispino, Marianna, Perrone-Capano, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356071/
https://www.ncbi.nlm.nih.gov/pubmed/25814944
http://dx.doi.org/10.3389/fnbeh.2015.00062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356071/
https://www.ncbi.nlm.nih.gov/pubmed/25814944
http://dx.doi.org/10.3389/fnbeh.2015.00062

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