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The transcription factor FOXL2 mobilizes estrogen signaling to maintain the identity of ovarian granulosa cells

FOXL2 is a lineage determining transcription factor in the ovary, but its direct targets and modes of action are not fully characterized. In this study, we explore the targets of FOXL2 and five nuclear receptors in murine primary follicular cells. We found that FOXL2 is required for normal gene regu...

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Detalles Bibliográficos
Autores principales: Georges, Adrien, L'Hôte, David, Todeschini, Anne Laure, Auguste, Aurélie, Legois, Bérangère, Zider, Alain, Veitia, Reiner A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356143/
https://www.ncbi.nlm.nih.gov/pubmed/25369636
http://dx.doi.org/10.7554/eLife.04207