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Modulation of Immune Cell Functions by the E3 Ligase Cbl-b

Maintenance of immunological tolerance is a critical hallmark of the immune system. Several signaling checkpoints necessary to balance activating and inhibitory input to immune cells have been described so far, among which the E3 ligase Cbl-b appears to be a central player. Cbl-b is expressed in all...

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Detalles Bibliográficos
Autores principales: Lutz-Nicoladoni, Christina, Wolf, Dominik, Sopper, Sieghart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356231/
https://www.ncbi.nlm.nih.gov/pubmed/25815272
http://dx.doi.org/10.3389/fonc.2015.00058