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Synergistic cytotoxicity of cisplatin and Taxol in overcoming Taxol resistance through the inhibition of LDHA in oral squamous cell carcinoma

The development of chemoresistance in patients represents a major challenge in cancer treatment. Lactate dehydrogenase-A (LDHA) is one of the principle isoforms of LDH that is expressed in breast tissue, controlling the conversion of pyruvate to lactate and also playing a significant role in the met...

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Detalles Bibliográficos
Autores principales: FENG, LIN, E, LING-LING, SOLOVEIV, MICHAIL MICHAILOVICH, WANG, DONG-SHENG, ZHANG, BO, DONG, YU WAN, LIU, HONG-CHEN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356296/
https://www.ncbi.nlm.nih.gov/pubmed/25789051
http://dx.doi.org/10.3892/ol.2015.2931