Effects of targeted phosphorylation site mutations in the DNA-PKcs phosphorylation domain on low and high LET radiation sensitivity

The present study investigated the effect of targeted mutations in the DNA-dependent protein kinase catalytic subunit and phosphorylation domains on the survival of cells in response to different qualities of ionizing radiation. Mutated Chinese hamster ovary V3 cells were exposed to 500 MeV/nucleon...

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Detalles Bibliográficos
Autores principales: CARTWRIGHT, IAN M., BELL, JUSTIN J., MAEDA, JUNKO, GENET, MATTHEW D., ROMERO, ASHLEY, FUJII, YOSHIHIRO, FUJIMORI, AKIRA, KITAMUTA, HISASHI, KAMADA, TADASHI, CHEN, DAVID J., KATO, TAKAMITSU A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356358/
https://www.ncbi.nlm.nih.gov/pubmed/25789011
http://dx.doi.org/10.3892/ol.2015.2974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356358/
https://www.ncbi.nlm.nih.gov/pubmed/25789011
http://dx.doi.org/10.3892/ol.2015.2974

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