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Promoter methylation and expression changes of BRCA1 in cancerous tissues of patients with sporadic breast cancer

BRCA1 is a susceptibility gene that has a genetic predisposition for breast cancer. BRCA1 gene mutation is closely associated with familial hereditary breast cancer, but the BRCA1 gene mutation is rarely found in sporadic breast cancer. According to previous studies, decreased expression of BRCA1 wa...

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Detalles Bibliográficos
Autores principales: LI, QIUYUN, WEI, WEI, JIANG, YI, YANG, HUAWEI, LIU, JIANLUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356378/
https://www.ncbi.nlm.nih.gov/pubmed/25789047
http://dx.doi.org/10.3892/ol.2015.2908