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Osteopontin-c mediates the upregulation of androgen responsive genes in LNCaP cells through PI3K/Akt and androgen receptor signaling

Androgen receptor (AR) signaling is a key pathway modulating prostate cancer (PCa) progression. Several steps in this pathway have been investigated in order to propose novel treatment strategies for advanced PCa. Total osteopontin (OPN) has been described as a biomarker for PCa, in addition to its...

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Detalles Bibliográficos
Autores principales: TILLI, TATIANA MARTINS, FERREIRA, LUCIANA BUENO, GIMBA, ETEL RODRIGUES PEREIRA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356391/
https://www.ncbi.nlm.nih.gov/pubmed/25789054
http://dx.doi.org/10.3892/ol.2015.2939