Role of Drosophila EDEMs in the degradation of the alpha-1-antitrypsin Z variant

The synthesis of proteins in the endoplasmic reticulum (ER) that exceeds the protein folding capacity of this organelle is a frequent cause of cellular dysfunction and disease. An example of such a disease is alpha-1-antitrypsin (A1AT) deficiency, caused by destabilizing mutations in this glycoprote...

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Detalles Bibliográficos
Autores principales: JANG, BO-YUN, RYOO, HYUNG DON, SON, JAEKYOUNG, CHOI, KYUNG-CHUL, SHIN, DONG-MYOUNG, KANG, SANG-WOOK, KANG, MIN-JI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356437/
https://www.ncbi.nlm.nih.gov/pubmed/25716426
http://dx.doi.org/10.3892/ijmm.2015.2109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356437/
https://www.ncbi.nlm.nih.gov/pubmed/25716426
http://dx.doi.org/10.3892/ijmm.2015.2109

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