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Aurora kinase A has a significant role as a therapeutic target and clinical biomarker in endometrial cancer

Aurora kinase A (AURKA) regulates the cell cycle checkpoint and maintains genomic integrity. AURKA is overexpressed in various malignant tumors and its upregulation induces chromosomal instability, which leads to aneuploidy and cell transformation. To investigate the role of AURKA in endometrial can...

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Detalles Bibliográficos
Autores principales: UMENE, KIYOKO, YANOKURA, MEGUMI, BANNO, KOUJI, IRIE, HARUKO, ADACHI, MASATAKA, IIDA, MIHO, NAKAMURA, KANAKO, NOGAMI, YUYA, MASUDA, KENTA, KOBAYASHI, YUSUKE, TOMINAGA, EIICHIRO, AOKI, DAISUKE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356503/
https://www.ncbi.nlm.nih.gov/pubmed/25625960
http://dx.doi.org/10.3892/ijo.2015.2842