Angiopoietin-1 Requires Oxidant Signaling through p47phox to Promote Endothelial Barrier Defense

BACKGROUND: Reactive oxygen species (ROS) are largely considered to be pathogenic to normal endothelial function in disease states such as sepsis. We hypothesized that Angiopoietin-1 (Angpt-1), an endogenous agonist of the endothelial-specific receptor, Tie-2, promotes barrier defense by activating...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghosh, Chandra C., Mukherjee, Aditi, David, Sascha, Milam, Katelyn E., Hunter, Jon T., Parikh, Samir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356555/
https://www.ncbi.nlm.nih.gov/pubmed/25761062
http://dx.doi.org/10.1371/journal.pone.0119577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356555/
https://www.ncbi.nlm.nih.gov/pubmed/25761062
http://dx.doi.org/10.1371/journal.pone.0119577

Ejemplares similares