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NLRP3 Mediates NF-κB Activation and Cytokine Induction in Microbially Induced and Sterile Inflammation

Nucleotide-binding domain and leucine-rich repeat-containing family, pyrin domain containing 3 (NLRP3) has recently emerged as a central regulator of innate immunity and inflammation in response to both sterile inflammatory and microbial invasion signals. Although its ability to drive proteolytic pr...

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Detalles Bibliográficos
Autores principales: Kinoshita, Takeshi, Imamura, Ryu, Kushiyama, Hiroko, Suda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356585/
https://www.ncbi.nlm.nih.gov/pubmed/25761061
http://dx.doi.org/10.1371/journal.pone.0119179