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Establishment of HSV1 Latency in Immunodeficient Mice Facilitates Efficient In Vivo Reactivation

The establishment of latent infections in sensory neurons is a remarkably effective immune evasion strategy that accounts for the widespread dissemination of life long Herpes Simplex Virus type 1 (HSV1) infections in humans. Periodic reactivation of latent virus results in asymptomatic shedding and...

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Detalles Bibliográficos
Autores principales: Ramakrishna, Chandran, Ferraioli, Adrianna, Calle, Aleth, Nguyen, Thanh K., Openshaw, Harry, Lundberg, Patric S., Lomonte, Patrick, Cantin, Edouard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356590/
https://www.ncbi.nlm.nih.gov/pubmed/25760441
http://dx.doi.org/10.1371/journal.ppat.1004730