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Establishment of HSV1 Latency in Immunodeficient Mice Facilitates Efficient In Vivo Reactivation
The establishment of latent infections in sensory neurons is a remarkably effective immune evasion strategy that accounts for the widespread dissemination of life long Herpes Simplex Virus type 1 (HSV1) infections in humans. Periodic reactivation of latent virus results in asymptomatic shedding and...
Autores principales: | Ramakrishna, Chandran, Ferraioli, Adrianna, Calle, Aleth, Nguyen, Thanh K., Openshaw, Harry, Lundberg, Patric S., Lomonte, Patrick, Cantin, Edouard M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356590/ https://www.ncbi.nlm.nih.gov/pubmed/25760441 http://dx.doi.org/10.1371/journal.ppat.1004730 |
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