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Engineering More Stable, Selectable Marker-Free Autoluminescent Mycobacteria by One Step
In our previous study, we demonstrated that the use of the autoluminescent Mycobacterium tuberculosis as a reporter strain had the potential to drastically reduce the time, effort, animals and costs consumed in evaluation of the activities of drugs and vaccines in live mice. However, the strains wer...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356594/ https://www.ncbi.nlm.nih.gov/pubmed/25760622 http://dx.doi.org/10.1371/journal.pone.0119341 |