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Antibiotic Treatment of Severe Exacerbations of Chronic Obstructive Pulmonary Disease with Procalcitonin: A Randomized Noninferiority Trial

BACKGROUND: The duration of antibiotic treatment of exacerbations of COPD (ECOPD) is controversial. Serum procalcitonin (PCT) is a biomarker of bacterial infection used to identify the cause of ECOPD. METHODS AND FINDINGS: We investigated whether a PCT-guided plan would allow a shorter duration of a...

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Detalles Bibliográficos
Autores principales: Verduri, Alessia, Luppi, Fabrizio, D’Amico, Roberto, Balduzzi, Sara, Vicini, Roberto, Liverani, Anna, Ruggieri, Valentina, Plebani, Mario, Barbaro, Maria Pia Foschino, Spanevello, Antonio, Canonica, Giorgio Walter, Papi, Alberto, Fabbri, Leonardo Michele, Beghè, Bianca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356612/
https://www.ncbi.nlm.nih.gov/pubmed/25760346
http://dx.doi.org/10.1371/journal.pone.0118241