Cargando…

Antibiotic Treatment of Severe Exacerbations of Chronic Obstructive Pulmonary Disease with Procalcitonin: A Randomized Noninferiority Trial

BACKGROUND: The duration of antibiotic treatment of exacerbations of COPD (ECOPD) is controversial. Serum procalcitonin (PCT) is a biomarker of bacterial infection used to identify the cause of ECOPD. METHODS AND FINDINGS: We investigated whether a PCT-guided plan would allow a shorter duration of a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Verduri, Alessia, Luppi, Fabrizio, D’Amico, Roberto, Balduzzi, Sara, Vicini, Roberto, Liverani, Anna, Ruggieri, Valentina, Plebani, Mario, Barbaro, Maria Pia Foschino, Spanevello, Antonio, Canonica, Giorgio Walter, Papi, Alberto, Fabbri, Leonardo Michele, Beghè, Bianca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356612/ https://www.ncbi.nlm.nih.gov/pubmed/25760346 http://dx.doi.org/10.1371/journal.pone.0118241

Ejemplares similares

Use of adjunct cardiovascular therapy in patients hospitalised for acute exacerbations of COPD
por: Roversi, Sara, et al.
Publicado: (2018)

Management of chronic refractory cough in adults
por: Visca, Dina, et al.
Publicado: (2020)

Echocardiography, Spirometry, and Systemic Acute-Phase Inflammatory Proteins in Smokers with COPD or CHF: An Observational Study
por: Beghé, Bianca, et al.
Publicado: (2013)

Rate of Decline of FEV(1) as a Biomarker of Survival?
por: Papi, Alberto, et al.
Publicado: (2021)

Breathlessness, but not cough, suggests chronic obstructive pulmonary disease in elderly smokers with stable heart failure
por: Roversi, Sara, et al.
Publicado: (2018)

Real-World Experience with Dupilumab in Severe Asthma: One-Year Data from an Italian Named Patient Program
por: Campisi, Raffaele, et al.
Publicado: (2021)

Models of Respiratory Infections: Virus-Induced Asthma Exacerbations and Beyond
por: Saturni, Sara, et al.
Publicado: (2015)

Type of adjuvant endocrine therapy and disease-free survival in patients with early HR-positive/HER2-positive BC: analysis from the phase III randomized ShortHER trial
por: Dieci, Maria Vittoria, et al.
Publicado: (2023)

Author Correction: Type of adjuvant endocrine therapy and disease-free survival in patients with early HR-positive/HER2-positive BC: analysis from the phase III randomized ShortHER trial
por: Dieci, Maria Vittoria, et al.
Publicado: (2023)

Serum Procalcitonin and Infective Exacerbations of Asthma
por: D'silva, Liesel, et al.
Publicado: (2011)

Defining the noninferiority margin and analysing noninferiority: An overview
por: Althunian, Turki A., et al.
Publicado: (2017)

Symptom versus exacerbation control: an evolution in GINA guidelines?
por: Latorre, Manuela, et al.
Publicado: (2023)

Noninferiority trials
por: Snapinn, Steven M
Publicado: (2000)

Prevalence of asthma and COPD in a cohort of patients at the follow up after COVID-19 pneumonia
por: Verduri, A., et al.
Publicado: (2023)

Randomised controlled trial comparing efficacy and safety of high versus low Low-Molecular Weight Heparin dosages in hospitalized patients with severe COVID-19 pneumonia and coagulopathy not requiring invasive mechanical ventilation (COVID-19 HD): a structured summary of a study protocol
por: Marietta, Marco, et al.
Publicado: (2020)

Understanding noninferiority trials
por: Hahn, Seokyung
Publicado: (2012)

Procalcitonin in patients with severe coronavirus disease 2019 (COVID-19): A meta-analysis
por: Lippi, Giuseppe, et al.
Publicado: (2020)

Are the Two Human Papillomavirus Vaccines Really Similar? A Systematic Review of Available Evidence: Efficacy of the Two Vaccines against HPV
por: Di Mario, Simona, et al.
Publicado: (2015)

Corrigendum to “Are the Two Human Papillomavirus Vaccines Really Similar? A Systematic Review of Available Evidence: Efficacy of the Two Vaccines against HPV”
por: Di Mario, Simona, et al.
Publicado: (2017)

Procalcitonin-Guided Antibiotic Use in Acute Exacerbations of Idiopathic Pulmonary Fibrosis
por: Ding, Juanjuan, et al.
Publicado: (2013)

Procalcitonin and CRP as Biomarkers in Discrimination of Community-acquired Pneumonia and Exacerbation of COPD
por: Çolak, Ayfer, et al.
Publicado: (2017)

Sputum procalcitonin levels in patients admitted to hospital with acute exacerbations of bronchiectasis
por: Good, William, et al.
Publicado: (2020)

Procalcitonin to guide antibiotic administration in COPD exacerbations: a meta-analysis
por: Mathioudakis, Alexander G., et al.
Publicado: (2017)

Noninferiority Testing in Clinical Trials
por: Ng, Tie-Hua
Publicado: (2014)

Omalizumab as add‐on therapy in a patient with severe asthma and OSA
por: Scioscia, Giulia, et al.
Publicado: (2020)

Clinical Factors Associated with a Shorter or Longer Course of Antibiotic Treatment in Patients with Exacerbations of Bronchiectasis: A Prospective Cohort Study
por: Scioscia, Giulia, et al.
Publicado: (2019)

MicroRNA expression profile during different conditions of hypoxia
por: Lacedonia, Donato, et al.
Publicado: (2018)

COPD, Pulmonary Fibrosis and ILAs in Aging Smokers: The Paradox of Striking Different Responses to the Major Risk Factors
por: Beghé, Bianca, et al.
Publicado: (2021)

Rivaroxaban was found to be noninferior to warfarin in routine clinical care: A retrospective noninferiority cohort replication study
por: Althunian, Turki A., et al.
Publicado: (2020)

Noninferiority Margin Size and Acceptance of Trial Results: Contingent Valuation Survey of Clinician Preferences for Noninferior Mortality
por: Pong, Sandra, et al.
Publicado: (2022)

Obstructive Sleep Apnea: A Look towards Micro-RNAs as Biomarkers of the Future
por: Moriondo, Giorgia, et al.
Publicado: (2022)

Serum Procalcitonin Level as a Predictor of Bacterial Infection in Patients with COPD Exacerbation
por: Abedini, Atefeh, et al.
Publicado: (2019)

Testing Statistical Hypotheses of Equivalence and Noninferiority
por: Wellek, Stefan
Publicado: (2010)

Nasal high-flow oxygen versus noninvasive ventilation in acute exacerbation of COPD: protocol for a randomised noninferiority clinical trial
por: Papalampidou, Athanasia, et al.
Publicado: (2020)

Procalcitonin levels in acute exacerbation of COPD admitted in ICU: a prospective cohort study
por: Daubin, Cédric, et al.
Publicado: (2008)

Value of procalcitonin, C-reactive protein, and neopterin in exacerbations of chronic obstructive pulmonary disease
por: Lacoma, Alicia, et al.
Publicado: (2011)

Procalcitonin guided antibiotic therapy of acute exacerbations of asthma: a randomized controlled trial
por: Tang, Jianguo, et al.
Publicado: (2013)

The role of serum procalcitonin and CRP levels in determining of etiology and outcome in acute exacerbations of COPD
por: Ceylan, O, et al.
Publicado: (2015)

Introduction of Procalcitonin Testing and Antibiotic Utilization for Acute Exacerbations of Chronic Obstructive Pulmonary Disease
por: Ulrich, Robert J, et al.
Publicado: (2019)

1479. Evaluating the Impact of Procalcitonin on Antibiotic Utilization in Chronic Obstructive Pulmonary Disease Exacerbations
por: Lin, Kevin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_anefq5pvjbmo7s8iaks0e2urib