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Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

Converging evidence implicates immune abnormalities in schizophrenia (SCZ), and recent genome-wide association studies (GWAS) have identified immune-related single-nucleotide polymorphisms (SNPs) associated with SCZ. Using the conditional false discovery rate (FDR) approach, we evaluated pleiotropy...

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Detalles Bibliográficos
Autores principales: Andreassen, O A, Harbo, H F, Wang, Y, Thompson, W K, Schork, A J, Mattingsdal, M, Zuber, V, Bettella, F, Ripke, S, Kelsoe, J R, Kendler, K S, O'Donovan, M C, Sklar, P, McEvoy, L K, Desikan, R S, Lie, B A, Djurovic, S, Dale, A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356743/
https://www.ncbi.nlm.nih.gov/pubmed/24468824
http://dx.doi.org/10.1038/mp.2013.195