Improving the consistency of domain annotation within the Conserved Domain Database

When annotating protein sequences with the footprints of evolutionarily conserved domains, conservative score or E-value thresholds need to be applied for RPS-BLAST hits, to avoid many false positives. We notice that manual inspection and classification of hits gathered at a higher threshold can add...

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Detalles Bibliográficos
Autores principales: Derbyshire, Myra K., Gonzales, Noreen R., Lu, Shennan, He, Jane, Marchler, Gabriele H., Wang, Zhouxi, Marchler-Bauer, Aron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356950/
https://www.ncbi.nlm.nih.gov/pubmed/25767294
http://dx.doi.org/10.1093/database/bav012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356950/
https://www.ncbi.nlm.nih.gov/pubmed/25767294
http://dx.doi.org/10.1093/database/bav012

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