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Allostery through protein-induced DNA bubbles

Allostery through DNA is increasingly recognized as an important modulator of DNA functions. Here, we show that the coalescence of protein-induced DNA bubbles can mediate allosteric interactions that drive protein aggregation. We propose that such allostery may regulate DNA's flexibility and th...

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Detalles Bibliográficos
Autores principales: Traverso, Joseph J., Manoranjan, Valipuram S., Bishop, A. R., Rasmussen, Kim Ø., Voulgarakis, Nikolaos K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356955/
https://www.ncbi.nlm.nih.gov/pubmed/25762409
http://dx.doi.org/10.1038/srep09037