Cargando…

Characterization of the MCM homohexamer from the thermoacidophilic euryarchaeon Picrophilus torridus

The typical archaeal MCM exhibits helicase activity independently in vitro. This study characterizes MCM from the euryarchaeon Picrophilus torridus. While PtMCM hydrolyzes ATP in DNA-independent manner, it displays very poor ability to unwind DNA independently, and then too only under acidic conditi...

Descripción completa

Detalles Bibliográficos
Autores principales: Goswami, Kasturi, Arora, Jasmine, Saha, Swati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356968/
https://www.ncbi.nlm.nih.gov/pubmed/25762096
http://dx.doi.org/10.1038/srep09057