Kirenol Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Differentiation of Th1 and Th17 Cells and Inducing Apoptosis of Effector T Cells

Experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis (MS), is characterized by CNS demyelination mediated by autoreactive T cells. Kirenol, a biologically active substance isolated from Herba Siegesbeckiae, has potent anti-inflammatory activities. Here we investigated effec...

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Detalles Bibliográficos
Autores principales: Xiao, Juan, Yang, Rongbing, Yang, Lin, Fan, Xiaohang, Liu, Wenwei, Deng, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356981/
https://www.ncbi.nlm.nih.gov/pubmed/25762107
http://dx.doi.org/10.1038/srep09022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356981/
https://www.ncbi.nlm.nih.gov/pubmed/25762107
http://dx.doi.org/10.1038/srep09022

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