The Nuclear Receptor Nr4a1 Controls CD8 T Cell Development Through Transcriptional Suppression of Runx3

The NR4A nuclear receptor family member Nr4a1 is strongly induced in thymocytes undergoing selection, and has been shown to control the development of T(reg) cells; however the role of Nr4a1 in CD8(+) T cells remains undefined. Here we report a novel role for Nr4a1 in regulating the development and...

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Detalles Bibliográficos
Autores principales: Nowyhed, Heba N., Huynh, Tridu R., Blatchley, Amy, Wu, Runpei, Thomas, Graham D., Hedrick, Catherine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356985/
https://www.ncbi.nlm.nih.gov/pubmed/25762306
http://dx.doi.org/10.1038/srep09059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356985/
https://www.ncbi.nlm.nih.gov/pubmed/25762306
http://dx.doi.org/10.1038/srep09059

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