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Structure, Function and Inhibition of the Phosphoethanolamine Methyltransferases of the Human Malaria Parasites Plasmodium vivax and Plasmodium knowlesi

Phosphoethanolamine methyltransferases (PMTs) catalyze the three-step methylation of phosphoethanolamine to form phosphocholine, a critical step in the synthesis of phosphatidylcholine in a select number of eukaryotes including human malaria parasites, nematodes and plants. Genetic studies in the ma...

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Detalles Bibliográficos
Autores principales: Garg, Aprajita, Lukk, Tiit, Kumar, Vidya, Choi, Jae-Yeon, Augagneur, Yoann, Voelker, Dennis R., Nair, Satish, Mamoun, Choukri Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357015/
https://www.ncbi.nlm.nih.gov/pubmed/25761669
http://dx.doi.org/10.1038/srep09064