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Structure, Function and Inhibition of the Phosphoethanolamine Methyltransferases of the Human Malaria Parasites Plasmodium vivax and Plasmodium knowlesi
Phosphoethanolamine methyltransferases (PMTs) catalyze the three-step methylation of phosphoethanolamine to form phosphocholine, a critical step in the synthesis of phosphatidylcholine in a select number of eukaryotes including human malaria parasites, nematodes and plants. Genetic studies in the ma...
Autores principales: | Garg, Aprajita, Lukk, Tiit, Kumar, Vidya, Choi, Jae-Yeon, Augagneur, Yoann, Voelker, Dennis R., Nair, Satish, Mamoun, Choukri Ben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357015/ https://www.ncbi.nlm.nih.gov/pubmed/25761669 http://dx.doi.org/10.1038/srep09064 |
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