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Identification of subgroup-specific miRNA patterns by epigenetic profiling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma

BACKGROUND: Altered expression of microRNAs (miRNAs) commonly accompanies colorectal (CRC) and endometrial carcinoma (EC) development, but the underlying mechanisms and clinicopathological correlations remain to be clarified. We focused on epigenetic mechanisms and aimed to explore if DNA methylatio...

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Detalles Bibliográficos
Autores principales: Kaur, Sippy, Lotsari, Johanna E, Al-Sohaily, Sam, Warusavitarne, Janindra, Kohonen-Corish, Maija RJ, Peltomäki, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357086/
https://www.ncbi.nlm.nih.gov/pubmed/25767621
http://dx.doi.org/10.1186/s13148-015-0059-3